ms02g_PI ms02g_PG_al
6 C|T
6 T|C
6 A|C
6 G|T
×----------×----->×——————————×—————> Break Point
4 T|C
4 T|C
4 T|C
4 T|A
t ms02g_PG_al
P r ---- C|T
o a |||| T|C
s n |||| A|C
s s |||| G|T
i i |||| ×----->×—————> Break Point
b t |||- T|C
l i ||-- T|C
e o |--- T|C
n ---- T|A
t ms02g_PG_al
P r ---- C|T \
o a |||| T|C | Block 1
s n |||| A|C |
s s |||| G|T /
i i |||| ×----->×—————> Break Point
b t |||- T|C \
l i ||-- T|C |
e o |--- T|C | Block 2
n ---- T|A /
| |
v v
Hap A Hap B
Block-1-Hap-A with Block-2-Hap-B vs. Block-1-Hap-A with Block-2-Hap-A
C|C × C|C × C|C × A|C = 0.58612 T|C × T|C × T|C × T|C = 0.000244
+ C|T × C|T × C|T × A|T = 0.3164 + T|T × T|T × T|T × T|T = 0.00391
+ C|A × C|A × C|A × A|A = 0.482 + T|A × T|A × T|A × T|A = 0.0007716
+ C|G × C|G × C|G × A|G = 0.3164 + T|G × T|G × T|G × T|G = 0.00391
——————— —————————
Avg = 0.42523 Avg = 0.002207
Likelyhood Ratio = 0.42523 / 0.002207 = 192.67