Pretty clean looking code, but let's look at a few ways it could be better or more pythonic:

• Use elif statements:

    if personInput == randnumb:
        # ...
    elif personInput > randnumb:  # You already know they're != at this point
        # ...
    elif ...
  

• Use snake case for your variable names. E.g., use person_input instead of personInput (which is camel case), and rand_num instead of randnumb. In that second case, it's also more common to shorten "number" to "num" instead of "numb".

• Use format strings instead of print's argument concatenation, e.g.:

    print("Guess lower ({} guesses left)".format(max_guesses - guesses))
  

• Check for and handle errors:

    try:
        person_input = int(input("What is your guess? "))
    except ValueError:
        print("Not sure what you meant by that, please input an integer")
        continue
  

• I prefer to be more safe than sorry when handling my own incrementor, such as guesses, just in case I do something funky that lets it skip over max_guesses:

    # Since you "break" on correct answer, we don't need to check that again
    if guesses >= max_guesses:
        # ...
  

Pretty clean looking code, but let's look at a few ways it could be better or more pythonic:

• Use elif statements:

    if personInput == randnumb:
        # ...
    elif personInput > randnumb:  # You already know they're != at this point
        # ...
    elif ...
  

• Use snake case for your variable names. E.g., use person_input instead of personInput (which is camel case), and rand_num instead of randnumb. In that second case, it's also more common to shorten "number" to "num" instead of "numb".

• Use format strings instead of print's argument concatenation, e.g.:

    print("Guess lower ({} guesses left)".format(max_guesses - guesses))
  

• Check for and handle errors:

    try:
        person_input = int(input("What is your guess? "))
    except ValueError:
        print("Not sure what you meant by that, please input an integer")
        continue
  

• I prefer to be more safe than sorry when handling my own incrementor, such as guesses, just in case I do something funky that lets it skip over max_guesses:

    # Since you "break" on correct answer, we don't need to check that again
    if guesses >= max_guesses:
        # ...
  

EDIT:

One more thing. In Python, to write a script (rather than a module), you should check if __name__ == '__main__': as follows:

from random import randint

def main():
    randnumb = randint(1,100)
    guesses = 0
    maxGuesses = 5
    
    while guesses < maxGuesses:
        # ...

if __name__ == '__main__':
    main()

This allows for safe code re-use, and makes sure that the code doesn't get run if this file gets imported from another file. It's not technically necessary for a one-file script like you're writing here, but it's a good practice to get into anyway.

Pretty clean looking code, but let's look at a few ways it could be better or more pythonic:

• Use elif statements:

if personInput == randnumb:
    # ...
elif personInput > randnumb:  # You already know they're != at this point
    # ...
elif ...

• Use snake case for your variable names. E.g., use person_input instead of personInput (which is camel case), and rand_num instead of randnumb. In that second case, it's also more common to shorten "number" to "num" instead of "numb".

• Use format strings instead of print's argument concatenation, e.g.:

print("Guess lower ({} guesses left)".format(max_guesses - guesses))

• Check for and handle errors:

try:
    person_input = int(input("What is your guess? "))
except ValueError:
    print("Not sure what you meant by that, please input an integer")
    continue

• I prefer to be more safe than sorry when handling my own incrementor, such as guesses, just in case I do something funky that lets it skip over max_guesses:

# Since you "break" on correct answer, we don't need to check that again
if guesses >= max_guesses:
    # ...

Pretty clean looking code, but let's look at a few ways it could be better or more pythonic:

• Use elif statements:

    if personInput == randnumb:
        # ...
    elif personInput > randnumb:  # You already know they're != at this point
        # ...
    elif ...
  

• Use snake case for your variable names. E.g., use person_input instead of personInput (which is camel case), and rand_num instead of randnumb. In that second case, it's also more common to shorten "number" to "num" instead of "numb".

• Use format strings instead of print's argument concatenation, e.g.:

    print("Guess lower ({} guesses left)".format(max_guesses - guesses))
  

• Check for and handle errors:

    try:
        person_input = int(input("What is your guess? "))
    except ValueError:
        print("Not sure what you meant by that, please input an integer")
        continue
  

• I prefer to be more safe than sorry when handling my own incrementor, such as guesses, just in case I do something funky that lets it skip over max_guesses:

    # Since you "break" on correct answer, we don't need to check that again
    if guesses >= max_guesses:
        # ...