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A test file for decompression can be found here (~42 MB). Python needs ~22 seconds to decompress it, while C# only requires ~2 seconds. When decompressed successfully, it results in a 4000x4000 bitmap looking like this:

However, being a little unsure about the "optimal" usage of IO classes and functions in Python, I got a little speed problem. The code run in Python is 10 times slower than the C# equivalent, and I don't find any more optimization potential, because of my limited Python knowledge.

I hope this question is not too broad and requires too much work... some general optimization tips when using BytesIO (or using a class suiting this case better?) would be great already!

However, being a little unsure about the "optimal" usage of IO classes and functions in Python, I got a little speed problem. The code runs 10 times slower in Python compared to the C# equivalent, and I don't find any more optimization potential, because of my limited Python knowledge.

I hope this question is not too broad and doesn't require too much work... some general optimization tips when using BytesIO (or using a class suiting this case better?) would be great already!